PERSONNEL

Dr. Bill R. Thomas


Research Scientist USRA, MSFC
Research Scientist CMMR, UAH

Alliance for Microgravity Materials Science and Applications
Universities Space Research Association
ES76 Space Sciences Laboratory
Marshall Space Flight Center, AL 35812

Phone: (256) 544 1386 or (256) 544 5854
Email: bill.thomas@msfc.nasa.gov

Center for Microgravity and Materials Research
University of Alabama in Huntsville
Huntsville, AL 35899

Office: RI D-8
Phone: (256) 824 6965 or (256) 824 6962
Fax: (256) 824 6944
Email: brtprotein@aol.com

Educational Background

Ph.D. Biology, Mississippi State University.
M.S. Biochemistry, Mississippi State University.
B.S. Biology, University of Mississippi.

Recent Professional Experience

Universities Space Research Association: Senior Research Scientist 1997-present
University of Alabama in Huntsville: Senior Research Scientist, Center for Microgravity and Materials Research 1995-1997
Merck & Co., Inc.: Senior Investigator 1991-1995

Professional Interests

Characterization, purification and crystallization of proteins and macromolecules.
High performance capillary electrophoresis of small molecules (drugs) and proteins.
High performance liquid chromatography.

Recent Publications

  • D.C. Carter, K. Lim , J.X. Ho, B.S. Wright, P.D. Twigg, T.Y. Miller, J. Chapman, K. Keeling, J. Ruble, P.G. Vekilov, B.R. Thomas, F. Rosenberger and A.A. Chernov, Lower Dimer Impurity Incorporation May Result in Higher Perfection of HEWL Crystals Grown in Microgravity: A Case Study, J. Crystal Growth 196 (1999) 623-637.
  • P.G. Vekilov, F. Rosenberger, H. Lin and B.R. Thomas, Nonlinear Dynamics of Layer Growth and Consequences for Protein Crystal Perfection, J. Crystal Growth 196 (1999) 261-275.
  • P.G. Vekilov, B.R. Thomas and F. Rosenberger, Effects of Convective Solute and Impurity Transport in Protein Crystal Growth, J. Physical Chem. B 102 (1998) 5208-5216.
  • B.R. Thomas, P. Vekilov and F. Rosenberger, Effect of Microheterogeneity on Hen Egg White Lysozyme Crystallization, Acta Crystallogr. D54 (1998) 226-236.
  • B.R. Thomas, D. Carter and F. Rosenberger, Effect of Microheterogeneity on Horse Spleen Apoferritin Crystallization, J. Crystal Growth 187 (1998) 499-510.
  • F. Rosenberger, M. Muschol, B.R. Thomas and P.G. Vekilov, Nucleation and Crystallization of Globular Proteins - What Do We Know and What Is Missing?, J. Crystal Growth 168 (1996) 1-27.
  • B.R. Thomas, P.G. Vekilov and F. Rosenberger, Heterogeneity Determination and Purification of Commercial Hen Egg White Lysozyme, Acta Crystallogr. D52 (1996) 776-784.
  • P.G. Vekilov, L.A. Monaco, B.R. Thomas, V. Stojanoff and F. Rosenberger, Repartitioning of NaCl and Protein Impurities in Lysozyme Crystallization, Acta Crystallogr. D52 (1996) 785-789.

  • 12.Dec.00