| PERSONNEL |
Dr. Peter G. Vekilov
Center for Microgravity and Materials Research |
 |
Moscow State University, M.S., Chemistry, 1985
Russian Academy of Sciences, Ph. D., Chemistry, 1991
Started at UAH in 1993
Undergraduate: Quantitative Analysis, Introduction to Chemistry,
Bipophysical Chemistry.
Graduate: Mechanisms of Nucleation and Growth of Phase Transitioons
Protein Crystallization
Physico-chemical aspects of sickle-cell anemia
Crystallization tools for structural genomics
Nucleation and phase transitions in protein solutions
Protein intermolecular interactions and phase diagrams
Criteria for the impact of reduced gravity on protein crystal perfection
Kinetics and Stability of Crystal Growth
Ph.D. Students
Angela Taylor, NIH-funded M.D./Ph.D. student: hemoglobin
crystallization
Kai Chen: AFM studies of protein crystal growth mechanims
Michelle Wu: phase transitions in protein solutions
Post-doctoral Associates
Dr. Dimiter Petsev: molecular interactions and aggregation in
solutions
Dr. Oleg Galkin: control of protein crystal nucleation
Dr. Nicolas Booth: stability of step trains in inorganic crystal
growth
Dr. Olga Gliko: step pattern formation in protein crystallization and effects of transport
conditions
Undergraduate Research Assistants
Sean Bohannon: interferometric setup for studies of the dynamics of step pattern
formation
Boris J. Stanojev: computer software for real-time image processing
Hunk Dang: light scattering investigations of protein molecular interactions
P.G. Vekilov and J.I.D. Alexander, Dynamics of layer growth in protein crystallization, Chem. Rev. 100 (2000), 2061-2089 [Table of Contents, PDF]
O. Galkin and P.G. Vekilov, Are nucleation kinetics of protein crystals similar to those of liquid droplets? J. Am. Chem. Soc. 122 (2000) 156-163 [Abstract, PDF]
D.N. Petsev and P.G. Vekilov, Evidence for non-DLVO hydration interactions in solutions of the protein apoferritin. Phys. Rev. Lett. 84 (2000) 1339-1342 [Abstract, PDF]
S.-T. Yau, B.R. Thomas and P.G. Vekilov, Molecular mechanisms of crystallization and defect formation. Phys. Rev. Lett. 85 (2000) 353-356 [Abstract, PDF]
O. Galkin and P.G. Vekilov, Control of protein crystal nucleation around the metastable liquid-liquid phase boundary, Proc. Natl. Acad. Sci. USA 97 (2000) 6277-6281 [Abstract, PDF]
S.-T. Yau and P.G. Vekilov, Quasi-planar nuclus structure in apoferritin crystallization, Nature 406 (2000) 494-497 [First Paragraph, PDF, N&V]
S.-T. Yau, D.N. Petsev, B.R. Thomas, and P.G. Vekilov, Molecular-level thermodynamic and kinetic parameters for the self-assembly of apoferritin molecules into crystals, J. Mol. Biol. 303 (2000) 667-678 [PDF]
12.Dec.2000